CENAS

Login

Dr. Babita Paudel

Head, Research Director
Balkhu, Kathmandu

ACADEMIC QUALIFICATION

                                      2009               Ph.D. (Biology), Soonchunhyang University, South Korea

 Title of Dissertation- Isolation and Characterization of Antibacterial and                                               Antioxidant compounds from the Antartic Lichen Ramalina terebrata

                                      2005               M.Sc. (Botany) Tribhuvan University, Kathmandu, Nepal

2003              B.Sc. (Biology) Tribhuvan University, Kathmandu, Nepal

 

Research Interest

  • Pharmacological study of medicinal plants and micro-organisms.
  • Isolation and Characterization of bioactive (antioxidant, antifungal, antimicrobial, anticancer, antifouling) secondary metabolites from Bacteria, Fungi, Lichens, Medicinal Plants and endophytic organisms.

 

Work Experiences

  1. Founder and Research Director (January 2018-date) Center for Natural and Applied Sciences (CENAS), Madan Nagar, Balkhu, Kathmandu, Nepal.
  2. Research Director (January 2014-2017) Research Institute of Bioscience and Biotechnology, RIBB, Nakkhu, Lalitpur, Nepal.

Project: Isolation and Characterization of antimicrobial, antioxidant and anticancer compounds from Lichen and their endophytes, Medicinal Plants and Streptomyces sp. of high altitudes regions of Nepal.

  1. Postdoctoral Fellow (January, 2011- December, 2013) Division of Life Sciences, Korea Polar Research Institute, KOPRI, Incheon, South Korea.

Project: Isolation and Characterization of useful secondary metabolites from higher plants and microorganisms of Antarctica, Mongolia, Russia and Nepal.

  1. Georg Forster Postdoctoral Research Fellowship (Alexander von Humboldt Foundation, Germany) (December 2009-December 2010). Department of Organic Chemistry, University of Goettingen, Goettingen, Germany.

Project: Screening, Isolation and Characterization of antimicrobial, antioxidant and toxic compounds from the lichens and their endophytes of extreme environments of Nepal.

  1. Student in Trainee (May, 2007- December, 2008) Polar BioCenter, Korea Polar Research Institute, KOPRI, Incheon, South Korea.

Project: Isolation and Characterization of Antimicrobial and antioxidants compounds from Antarctic Lichens and Mosses.

  1. Research Assistant (March 2005- April 2007) Department of Marine Biotechnology, Soonchunhyang University, South Korea.

 

Publications

  1. Paudel, K. Bhattarai and H.D.Bhattarai. 2017 Antimicrobial and antioxidant activities of two polyketides from lichen-endophytic fungus Preussia sp. Zeitschrift für Naturforschung C (Accepted)
  2. Paudel, K. Bhattarai and H.D.Bhattarai.2017. Evaluation of antimicrobial, antioxidant and phytochemical screening of the bark extract of Oroxylumindicum. Botanica Oreantilis. Accepted.
  3. N. Jha, M. Shrestha, D. P. Pandey, T. Bhattarai, H. D. Bhattarai, B. Paudel. 2017.Investigation of antioxidant, antimicrobial and toxicity activities of lichens from high altitude regions of Nepal. BMC Complementary and Alternative Medicine.17:282-89.
  1. B. Paudel, H.D. Bhattarai, I.C. Kim, H.S. Lee, R. Sofronov, L. Ivanova, L. Poryadina, J.H. Yim. 2014. Estimation of antioxidant, antimicrobial activity and brine shrimp toxicity of plants collected from Oymyakon region of the Republic of Sakha (Yakutia), Russia. Biological Research. 47:1-6.
  2. H.D. Bhattarai, B. Paudel, H. Oh, I.C. Kim, J.H. Yim. 2013. A new fused tetracyclic heterocycle from Serratia sp. PAMC 25557 and its antioxidant activity. Phytochemistry Letter 6:536-538.
  3. B. Paudel, H. D. Bhattarai, D. P. Pandey, J. S. Hur, S. G. Hong, I. C. Kim, J.H. Yim .2012. Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal. Biological Research. 45:387-391.
  4. B. Paudel, H.D. Bhattarai, J.H.Yim. 2012. In vitro antioxidant activity of the Antarctic lichen Caloplaca regalis and its GC/MS based phytochemical analysis. J. Biomolecule Reconstruction. 9:15-23.
  5. B. Paudel, H. D. Bhattarai, H. Y. Koh, S. G. Lee, S. J. Han, H. K. Lee, H. Oh, H. W. Shin, J. H. Yim. 2011. Ramalin, a Novel Nontoxic Antioxidant Compound from the Antarctic Lichen Ramalina terebrata. Phytomedicine. 18:1285-1290.
  6. B. Paudel, H. D. Bhattarai, H. K. Lee, H. Oh, H.W. Shin and J. H. Yim. 2010. Antibacterial activity of ramalin, using acid and its three other derivatives isolated from the Antarctic lichen Ramalina terebrata. Zeitschrift für Naturforschung C. 65c: 34-38.
  7. H. D. Bhattarai, B. Paudel, H. K. Lee, H. Oh and J. H. Yim. 2009. In vitro Antioxidant Capacities of Two Benzonaphthoxanthenones: Ohioensins F and G Isolated from the Antarctic Moss Polytrichastrum alpinum. Zeitschrift für Naturforschung C. 64c: 197-200.
  8. H. D. Bhattari, B. Paudel, H.S. Lee, Y. K. Lee and J. H. Yim. 2008. Antioxidant activity of Sanionia uncinata, a polar moss species from King George Island, Antarctica. Phytotherapy Research. 22:1635-1639.
  9. H. D. Bhattarai, B. Paudel, S. G. Hong, H. K. Lee and J. H. Yim. 2008. Thin    layer chromatography (TLC) analysis of antioxidant constituents of lichens from Antarctica. Journal of Natural Medicines. 62:481-484.
  10. B. Paudel, H. D. Bhattarai, J.S. Lee, S. G. Hong, H.W. Shin, J. H. Yim. 2008. Antioxidant activity of polar lichens from King George Island (Antarctica). Polar Biology. 31: 605-608.
  11. B. Paudel, H. D. Bhattarai, J.S. Lee, S. G. Hong, H.W. Shin, J. H. Yim. 2008. Antibacterial potential of Antarctic Lichens against Human Pathogenic Gram Positive Bacteria. Phytotherapy Research. 22: 1269-1271.
  12. H. D. Bhattarai, B. Paudel, N. S. Park and H. W. Shin. 2007. Evaluation of antifouling activity of eight commercially available organic chemicals against the early foulers- marine bacteria and Ulva spores. Journal of Environmental Biology. 28: 857-863.
  13. H. D. Bhattarai, B. Paudel, Y. K. Hong and H.W. Shin. 2007. A simple method to preserve algal spores of Ulva spp. in cold storage with ampicillin. Hydrobiologia. 5 92:399-404.
  14. H. D. Bhattarai, G. S.Viswanadh, B. Paudel., Y. K. Lee, H. K. Lee, Y.K. Hong and H. W. Shin. 2007. Isolation of antifouling compounds from the marine bacterium, Shewanella oneidensis SCH002. World Journal of Microbiology and Biotechnology. 23:243-249.

Patents:

  1. Yim, J.H., Lee, H.K., Bhattarai. H.D. B., Kim I.C., Hong S.G., Kim, D.K., Lee, Y.K., Lee, S.G., Oh, H.C. 2010. Novel compound ramalin and use thereof. International patent. WO/2010/053327.
  2. Yim, J.H., Kim, I.C., Han S.J., Kim H.O., Kim D., Paudel, B., Bhattarai. H.D. Antioxidant Compound Isolated from Serratia sp. and Use Thereof. Korean Patent.

 

Grants and Awards

  1. IFS (International Foundation for Science) Grant (Sweden) (January, 2015) on Investigation of antimicrobial, anticancer and antioxidant secondary metabolites from lichens and their endophytes from high altitude regions of Nepal.
  2. Alexander von Humboldt Foundation (Germany) Equipment Grant (January 2015) on Exploration of novel antibiotics, antioxidants and anticancer compounds from micro-organisms (bacteria, fungi, lichens) collected from extreme environments of mountainous regions of Nepal.
  1. TWAS (The World Academy of Science) Grant (Italy) (December, 2014) on Investigation of pathogenic bacteria and their biofilm composition in oral cavity of Nepalese population from different geographic location and analysis of its impacts on distribution, genetic variation, and pathogenic potential.
  1. IFS (International Foundation for Science) Grant (Sweden) (January, 2013) on Investigation of antimicrobial, anticancer and antioxidant secondary metabolites from lichens and their endophytes from high altitude regions of Nepal.

 

error: Content is protected !!
Scroll to Top